| Dear Dr. [CUSTOMFIELD1], | | Does your current work require the generation of custom monoclonal antibodies? If so, we would be glad to perform this tedious and time-consuming task on your behalf. | | We understand that people may designed/ordered one or two antigens for antibodies production, after 5-7 months of passionately waiting and testing, none of them really works well. They may have to wait another half a year for another shot, with finger crossed. We are very confident that our multiple antigens library strategy can greatly change this frustration. | | Our idea is very straight-forward, we normally use a number of antigens (as many as 20 protein fragments and/or peptides) instead of just one or two, the diverse antigens may cover all the best possible regions of the target protein for antibody production, thus almost maximize the successful rate of developing well-performing antibodies. This strategy is especially helpful for the “difficult” proteins like membrane proteins, nucleoprotein and high-end applications such as ChIP and flow cytometry. | | As of this date, we have supplied over a thousand laboratories around the world with antibodies for Western blot, IF, IHC, IP and flow cytometry. However, we are much more eager to hear about your works, your accomplishments and your special antibody needs. If there is anything we could do to serve your antibody need, please feel free to let us know the target protein. We will have our science team make an in-depth analysis on antibody-making startegy. | | Custom antibody development with successful end-uses in mind | | Protein Family | End-uses | Recommend Package | Successful Case | | Membrane proteins (receptors, ion channels), Kinases, Regulatory proteins, Transcription factors | WB | Input: 10 peptide antigens
Output: ~20 mAbs | Klfd (transcription factor):
Blood 113, 1340-1349 | | IF, IHC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | ASH-2 (member of H3K4me3 complex):
Nature 466, 383-387 | IP/ChIP
FC | Input: 11 peptide + 1 protein antigens
Output: ~30 mAbs | TCP (transcription factor):
The Plant Journal 71, 99-107 | | Cytoskeleton, Structural proteins, Enzymes, Heat-shock proteins | WB | Input: 6 peptide antigens
Output: ~12 mAbs | VP5(viral outer shell protein)
Virology Journal 8:132 | | IF, IHC | Input: 10 peptide antigens
Output: ~20 mAbs | zebrafish Raldh2 (de-hydrogenase):
Nature 464, 601-605 | IP/ChIP
FC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | Coco (secreted antagonist of TGF-beta):
Cell 150, 764-779 |
| | >>Visit our website for more detail << | Best wishes,
Sam Wong, Ph.D.
Business Development Manager
Backup email: sam.wong.abmart3@gmail.com
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