| Dear Dr. [CUSTOMFIELD1], | | If you have any interest in custom antibodies, please let us help you with our revolutionary technology that greatly boosts the end-use success rates of custom monoclonal antibodies. | | We believe for most proteins, there are a certain number of regions could be promising antigens to produce high-quality antibodies. To maximize the chance of success, we usually apply a number of antigens (up to 20 protein fragments and/or peptides) instead of just one or two; the diverse antigens could map all the best possible regions of the target protein. | | Based on our data from more than two thousand projects, in average, successful rate of applying 1 antigen is only 30%, whereas for 6 antigens is nearly 60%, and 10 antigens 70%. That is a clear demonstration of the power of multiplicity! This strategy is especially helpful for the “difficult” proteins like multi-pass transmembrane proteins. | | As of this date, we have supplied over a thousand laboratories around the world with antibodies for Western blot, IF, IHC, IP and flow cytometry. However, we are much more eager to hear about your works, your accomplishments and your special antibody needs. If there is anything we could do to serve your antibody need, please feel free to let us know the target protein. We will have our science team make an in-depth analysis on antibody-making startegy. | | Custom mAbs discovery with end-uses in mind | | Protein Family | End-uses | Recommend Package | Successful Case | | Membrane proteins (receptors, ion channels), Kinases, Regulatory proteins, Transcription factors | WB | Input: 10 peptide antigens
Output: ~20 mAbs | Klfd (transcription factor):
Blood 113, 1340-1349 | | IF, IHC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | ASH-2 (member of H3K4me3 complex):
Nature 466, 383-387 | IP/ChIP
FC | Input: 11 peptide + 1 protein antigens
Output: ~30 mAbs | TCP (transcription factor):
The Plant Journal 71, 99-107 | | Cytoskeleton, Structural proteins, Enzymes, Heat-shock proteins | WB | Input: 6 peptide antigens
Output: ~12 mAbs | VP5(viral outer shell protein)
Virology Journal 8:132 | | IF, IHC | Input: 10 peptide antigens
Output: ~20 mAbs | zebrafish Raldh2 (de-hydrogenase):
Nature 464, 601-605 | IP/ChIP
FC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | Coco (secreted antagonist of TGF-beta):
Cell 150, 764-779 |
| | >>Visit our website for more detail << | Best wishes,
Sam Wong, Ph.D.
Business Development Manager
Backup email: sam.wong.abmart3@gmail.com
| | Unsubscribe | Report Spam |
|