| Dear Dr. [CUSTOMFIELD1], | | If you have any interest in custom antibodies, please let us help you with our revolutionary technology that greatly boosts the end-use success rates of custom monoclonal antibodies. | | We believe for most proteins, there are a certain number of regions could be promising antigens to produce high-quality antibodies. To maximize the chance of success, we usually apply a number of antigens (up to 20 protein fragments and/or peptides) instead of just one or two; the diverse antigens could map all the best possible regions of the target protein. | | Based on our data from more than two thousand projects, in average, successful rate of applying 1 antigen is only 30%, whereas for 6 antigens is nearly 60%, and 10 antigens 70%. That is a clear demonstration of the power of multiplicity! This strategy is especially helpful for the “difficult” proteins like multi-pass transmembrane proteins. | | With our revolutionary techniques, within 3 months, by simply sending us the protein sequence, you will receive the tailor-made antibodies at only a fraction of current cost (e.g. USD1799 for 4-8 mAbs against 4 peptides of a protein). If you plan to raise antibodies against any protein target, please feel free to email me a sequence or accession number for an evaluation. Again, thank you for your interest. I wish you good luck with your work, and look forward to hearing from you. | | Custom mAbs discovery with end-uses in mind | | Protein Family | End-uses | Recommend Package | Successful Case | | Cytoskeleton, Structural proteins, Enzymes, Heat-shock proteins | WB | Input: 6 peptide antigens
Output: ~12 mAbs | VP5(viral outer shell protein)
Virology Journal 8:132 | | IF, IHC | Input: 10 peptide antigens
Output: ~20 mAbs | zebrafish Raldh2 (de-hydrogenase):
Nature 464, 601-605 | IP/ChIP
FC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | Coco (secreted antagonist of TGF-beta):
Cell 150, 764-779 | | Membrane proteins (receptors, ion channels), Kinases, Regulatory proteins, Transcription factors | WB | Input: 10 peptide antigens
Output: ~20 mAbs | Klfd (transcription factor):
Blood 113, 1340-1349 | | IF, IHC | Input: 7 peptide + 1 protein antigens
Output: ~22 mAbs | ASH-2 (member of H3K4me3 complex):
Nature 466, 383-387 | IP/ChIP
FC | Input: 11 peptide + 1 protein antigens
Output: ~30 mAbs | TCP (transcription factor):
The Plant Journal 71, 99-107 |
| | >>Visit our website for more detail << | Best wishes,
Sam Wong, Ph.D.
Business Development Manager
Backup email: sam.wong.abmart3@gmail.com
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